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1

ChemInform Abstract: 2-Phenylimidazo[1,2-b]pyridazine Derivatives Highly Active Against Haemonchus contortus.

Abdelselam Ali, Teresa Cablewski, Craig L. Francis, Ashit K. Ganguly, Roger M. Sargent, David G. Sawutz, Kevin N. Winzenberg

Journal:

Année:

2011

Fichier:

PDF, 24 KB

2011

2

Approach to the discovery of novel, selective inhibitors of p56lck tyrosine kinase: Identification of non-hydroxylated chromones as p56lck inhibitors

Deborah Miller, Su Wang, John Reid, Wen Xie, Bruce Gauvin, Marian Kelley, Jay Sarup, David G. Sawutz, Muhmut Miski, Roland E. Dolle, Connie R. Faltynek

Journal:

Drug Development Research

Année:

1995

Langue:

english

Fichier:

PDF, 779 KB

english, 1995

3

Role of bradykinin in inflammatory arthritis: Identification and functional analysis of bradykinin receptors on human synovial fibroblasts

Joanne Uhl, Saira Singh, Lynne Brophy, David Faunce, David G. Sawutz

Journal:

Immunopharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 620 KB

english, 1992

4

The effect of TNFa on bradykinin receptor binding, phosphatidylinositol turnover and cell growth in human A431 epidermoid carcinoma cells

David G. Sawutz, Saira S. Singh, Lorrie Tiberio, Edmond Koszewski, Cynthia G. Johnson, Carl L. Johnson

Journal:

Immunopharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 934 KB

english, 1992

5

[3H] 1,3-di(2-tolyl) guanidine binds to a σ2 receptor on Jurkat cell membranes, but σ compounds fail to influence immunomodulatory events in human peripheral blood lymphocytes

Diane L. Dehaven-Hudkins, Jeffrey D. Daubert, David G. Sawutz, Lorrie Tiberio, Yaela Baine

Journal:

Immunopharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 811 KB

english, 1996

6

Parasiticidal 2-alkoxy- and 2-aryloxyiminoalkyl trifluoromethanesulfonanilides

Abdelselam Ali, Timothy M. Altamore, Marianne Bliese, Petr Fisara, Andris J. Liepa, Adam G. Meyer, Oahn Nguyen, Roger M. Sargent, David G. Sawutz, David A. Winkler, Kevin N. Winzenberg, Angela Ziebell

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 121 KB

english, 2008

7

Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides

Abdelselam Ali, Petr Fisara, Jamie A. Freemont, Stella Kyi, Adam G. Meyer, Andrew G. Riches, Roger M. Sargent, David G. Sawutz, Kathleen A. Turner, Kevin N. Winzenberg, Qi Yang

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 312 KB

english, 2010

8

2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus

Abdelselam Ali, Teresa Cablewski, Craig L. Francis, Ashit K. Ganguly, Roger M. Sargent, David G. Sawutz, Kevin N. Winzenberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 365 KB

english, 2011

9

Synthesis and circular dichroism studies of steroidal schiff bases of biogenic amines

Howard C. Price, David G. Sawutz, Thomas E. Wagner, Chris Shewmaker

Journal:

Année:

1981

Langue:

english

Fichier:

PDF, 426 KB

english, 1981

10

Ace inhibitors as a template for the design of bradykinin B2 receptor antagonists

Denton Hoyer, Mohamed M.A. Awad, Joseph M. Salvino, Peter R. Seoane, Roland E. Dolle, Wayne T. Houck, David G. Sawutz

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 207 KB

english, 1995

11

Structure activity relationships of non-peptide bradykinin B2 receptor antagonists

Joseph M. Salvino, Peter R. Seoane, Brent D. Douty, Mohamed A. Awad, Denton Hoyer, Tina Morgan Ross, Roland E. Dolle, Wayne T. Houck, David M. Faunce, David G. Sawutz

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 290 KB

english, 1995

12

Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea)

Abdelselam Ali, Marianne Bliese, Jo-Anne M. Rasmussen, Roger M. Sargent, Simon Saubern, David G. Sawutz, John S. Wilkie, David A. Winkler, Kevin N. Winzenberg, Ruth C.J. Woodgate

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 142 KB

english, 2007

13

Characterization of bradykinin B2 receptors on human IMR-90 lung fibroblasts: Stimulation of 45Ca2+ efflux by D-Phe7 substituted bradykinin analogues

David G. Sawutz, David M. Fauncc, Wayne T. Houck, Dean Haycock

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 922 KB

english, 1992

14

Purification and characterization of the β2-adrenergic receptor from calf lung

Robert Insoft, David G. Sawutz, Charles J. Homcy

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1986

Langue:

english

Fichier:

PDF, 643 KB

english, 1986

15

Alpha1-adrenergic receptor photoaffinity labeling in intact cells

David G. Sawutz, Laureen M. Sena, Lawrence E. Cornett, Robert M. Graham

Journal:

Biochemical Pharmacology

Année:

1987

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1987

16

In vitro characterization of a novel series of platelet-derived growth factor receptor tyrosine kinase inhibitors

David G. Sawutz, Donald C. Bode, G.Maurice Briggs, John R. Reid, Paul Canniff, Lisa Caldwell, Connie R. Faltynek, Deborah Miller, Joseph A. Dunn, Lawrence de Garavilla, Joseph W. Guiles, Carolyn Weige

Journal:

Biochemical Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1011 KB

english, 1996

17

Effects of dimaprit on growth and differentiation of human promyelocytic cell line, HL-60

Karen A. Kalinyak, David G. Sawutz, Beatrice C. Lampkin, Carl L. Johnson, Jeffrey A. Whitsett

Journal:

Année:

1985

Langue:

english

Fichier:

PDF, 648 KB

english, 1985

18

High affinity binding of reovirus type 3 to cells that lack beta adrenergic receptor activity

David G. Sawutz, Rhonda Bassel-Duby, Charles J. Homcy

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 498 KB

english, 1987

19

Coupling of the α1-adrenergic receptor to a guanine nucleotide-binding regulatory protein by a discrete domain distinct from its ligand recognition site

Robert M. Graham, Laureen M. Sena, J.Peter Longabaugh, David G. Sawutz, Kurt R. Schwarz, Charles J. Homcy

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

1988

Langue:

english

Fichier:

PDF, 1002 KB

english, 1988

20

Synthesis and molecular characterization of a biotinylated analog of [Lys]bradykinin

David G. Sawutz, John Yanni, Marian Kelley, Henry Wolfe

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 554 KB

english, 1991

21

6-(4-Pyridinyl)-1H-1,2,3-triazolo[4,5-d]-pyrimidin-4(5H)-one: A Structurally Novel Competitive AMPA Receptor Antagonist

Subramanyam, Chakrapani, Ault, Brian, Sawutz, David, Bacon, Edward R., Singh, Baldev, Pennock, Patrick O., Kelly, Michael D., Kraynak, Matthew, Krafte, Doug, Treasurywala, Adi

Journal:

Journal of Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 290 KB

english, 1995

22

5,7-Dimethoxy-3-(4-Pyridinyl)Quinoline Is a Potent and Selective Inhibitor of Human Vascular .beta.-Type Platelet-Derived Growth Factor Receptor Tyrosine Kinase

Dolle, Roland E., Dunn, Joseph A., Bobko, Mark, Singh, Baldev, Kuster, Joan E., Baizman, Eugene, Harris, Alex L., Sawutz, David G., Miller, Deborah

Journal:

Journal of Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 428 KB

english, 1994

23

Enhanced antigen-antibody binding affinity mediated by an anti-idiotypic antibody

Sawutz, David G., Koury, Richard, Homcy, Charles J.

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 2.05 MB

english, 1987

24

Design of potent non-peptide competitive antagonists of the human bradykinin B2 receptor

Salvino, Joseph M., Seoane, Peter R., Douty, Brent D., Awad, Mohamad M. A., Dolle, Roland E., Houck, Wayne T., Faunce, David M., Sawutz, David G.

Journal:

Journal of Medicinal Chemistry

Année:

1993

Langue:

english

Fichier:

PDF, 275 KB

english, 1993

25

Synthesis, Characterization, and Conformational Analysis of the D/L-Tic7 Stereoisomers of Bradykinin Receptor Antagonist D-Arg0[Hyp3,Thi5,D-Tic7,Oic8]bradykinin

Sawutz, David G., Salvino, Joseph M., Seoane, Peter R., Douty, Brent D., Houck, Wayne T., Bobko, Mark A., Doleman, Muriel S., Dolle, Roland E., Wolfe, Henry R.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1994

26

AMPA (amino-3-hydroxy-5-methylisoxazole-4-propionic acid) Receptors in human brain tissues

Sawutz, David G., Krafte, Douglas S., Oleynek, Joseph J., Ault, Brian

Journal:

Journal of Receptor and Signal Transduction Research

Année:

1995

Langue:

english

Fichier:

PDF, 802 KB

english, 1995

27

Pharmacology and structure – activity relationships of the nonpeptide bradykinin receptor antagonist WIN 64338

Sawutz, David G., Salvino, Joseph M., Dolle, Ronald E., Seoane, Peter R., Farmer, Stephen G.

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 674 KB

english, 1995

28

The Nonpeptide WIN 64338 is a Bradykinin B2Receptor Antagonist

David G. Sawutz, Joseph M. Salvino, Roland E. Dolle, Fran Casiano, Susan J. Ward, Wayne T. Houck, David M. Faunce, Brent D. Douty, Eugene Baizman, Mohammed M. A. Awad, Francois Marceau and Peter R. Se

Journal:

Proceedings of the National Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1994